MyMedLab

NO FASTING is required for this test but you must still be consuming gluten prior to taking this test for it to be accurate..

The Celiac Disease Complete was designed to be an extensive evaluation for the presence of Celiac Disease.

Celiac Disease, also called Gluten-sensitive enteropathy, is a condition where when you eat foods with gluten, your immune system responds by damaging the small intestine. Gluten is a protein in wheat, rye and barley. It is found mainly in foods but may also be in other products.

Tests for Celiac Disease can be divided into 2 different types of antibodies: those which are anti-gluten, and those that anti-self. The anti-gluten antibodies are the anti-gliadin IgG and IgA. Ig stands for “immunoglobulin” or “antibody”.

The anti-self antibodies are anti-endomysial IgA and anti-tissue transglutaminase IgA. The tissue transglutaminase IgA antibody is often abbreviated as “tTG”. Each antibody test varies widely in its sensitivity and specificity for predicting whether the disease is present in any individual.

It must be remembered that NO test in medicine is correct 100% of the time in each person

The initial test results establish the baseline data used for comparison to future results. This profile includes the following tests. Click the test name for more information.

Anti-Self Tests

anti-Transglutaminase Antibodies (tTG IgA, tTG IgG)
anti-Endomysial Ab (Endomysial IGA)
Immunoglobulin A (Total IgA)

If the Tissue Transglutaminase IgA is positive, Endomysial Antibody Screen (IgA) will be performed. If the Endomysial Antibody Screen (IgA) is positive, Endomysial Antibody Titer will be performed. If the Total IgA is less than the lower limit of the reference range, based on age, Tissue Transglutaminase IgG will be performed.

Celiac disease affects each person differently. Symptoms may occur in the digestive system, or in other parts of the body. One person might have diarrhea and abdominal pain, while another person may be irritable or depressed. Irritability is one of the most common symptoms in children. Some people have no symptoms. Celiac disease is genetic. Blood tests can help your doctor diagnose the disease. Your doctor may also need to examine a small piece of tissue from your small intestine. Treatment is a diet free of gluten.